Sunday, February 13, 2011

Merek


Pansy 12:28 …your mentioning Crohn’s disease ,the following little known but effective proceedure have been cured of many digestive diseases ,The December 18th 2010 addition of the “New Scientist” has a great article on this proceedure that replaces the micro flora of digestion after Antibiotic treatments have destroyed the ability of the gut to absorbe nutrients.
Long post but very important:
“Fecal bacteriotherapyFrom Wikipedia, the free encyclopediaJump to: navigation, search
Fecal bacteria at 10,000× magnificationFecal bacteriotherapy, also known as fecal transfusion, fecal transplant, or human probiotic infusion (HPI), is a medical treatment for patients with pseudomembranous colitis (caused by Clostridium difficile), or ulcerative colitis which involves restoration of colon homeostasis by reintroducing normal bacterial flora from stool obtained from a healthy donor.
Contents [hide]
1 Description of procedure
2 Theoretical basis
3 Effectiveness
4 History
5 See also
6 External links
7 References
[edit] Description of procedureThe procedure itself sometimes involves a 5- to 10-day treatment with enemas, made of bacterial flora from feces of a healthy donor, though most patients recover after just one treatment[citation needed]. The best choice for donor is a close relative who has been tested for a wide array of bacterial and parasitic agents[1]. The enemas are prepared and administered in a hospital environment to ensure all necessary precautions. The probiotic infusion can also be administered through a nasogastric tube, delivering the bacteria directly to the small intestine[2]. The two methods can be combined to achieve the best result[citation needed]. Regular checkups are required up to a year following the procedure.
A modified form of fecal bacteriotherapy is being developed (Autologous Restoration of Gastrointestinal Flora – ARGF)[3]. which is safer, more effective and easier to administer. An autologous faecal sample, provided by the patient before medical treatment, is stored in a refrigerator. Should the patient subsequently develop C. difficile the sample is extracted with saline and filtered. The filtrate is freeze dried and the resulting solid enclosed in enteric coated capsules. Administration of the capsules will restore the patient’s own colonic flora and combat C. difficile. This procedure will avoid the hazards of standard FB where infection from the donor could be transmitted to the patient and the requirement to deliver faecal samples into the duodenum via a nasal probe.
[edit] Theoretical basisThe hypothesis behind fecal bacteriotherapy rests on the concept of bacterial interference: using harmless bacteria to displace pathogenic organisms. This approach to combating bacterial infections is not new[4], and has long been used in animals; for example, to prevent salmonellosis in chickens[5]. In the case of pseudomembranous colitis the pathogen is known (C. difficile), but since no single pathogen causing ulcerative colitis has been found so far, the effectiveness of fecal bacteriotherapy suggests that the cause of ulcerative colitis may be a previous infection by a still unknown pathogen. It is possible that this initial infection resolves itself naturally, but somehow causes an imbalance in the colonic bacterial flora, leading to a cycle of inflammation (explaining the remitting-relapsing nature of the disease) which can be broken by recolonizing the colon with bacteria from a healthy bowel[6]. This may be considered an extension of probiotic research.
[edit] EffectivenessThe procedure has been used in the treatment of C. difficile infections for a number of years, the body of literature examining its efficacy currently consists only of observational studies, and no randomized controlled trials.[7][8][9]. Benefits of fecal bacteriotherapy include reducing the risk of cultivating antibiotic-associated resistance in the pathogenic bacteria displaced by the colonization and its purported effectiveness when antibiotic resistance is already in place. It is still considered a “last resort” therapy due to its relative invasiveness compared to antibiotics, the inherent risks of infection, lack of Medicare coverage for donor stool screening and instillation procedure and the absence of any effective means of ensuring that the donor stool is itself free of pathogens.[1]
While its effects on ulcerative colitis have not yet been adequately researched, small case studies report has positive effects. A recent article by Borody et al. which details 6 cases of severe chronic ulcerative colitis treated using Fecal bacteriotherapy suggests that the procedure may be extremely successful in these cases as well. Complete reversal of symptoms was achieved in all patients by 4 months post-HPI, by which time all other UC medications had been ceased. At 1 to 13 years post-HPI and without any UC medication, there was no clinical, colonoscopic, or histologic evidence of UC in any patient[10]. The Sydney group also reports a case of presumed sclerosing cholangitis, a disease frequently associated with IBD, which recovered fully after the treatment.
Experiments are currently being conducted with Fecal bacteriotherapy as a treatment for Parkinsons disease, diabetes, and obesity [2].
[edit] HistoryIt has been developed in recent years by Dr. Thomas J. Borody and his team in Sydney, Australia, primarily as an alternative treatment for pseudomembranous colitis. This disease is caused by C. difficile infection,”
And Pansy ,I am not refering to the serious disease “Opti-rectitus” this condition springs from the optic nerves direct connection to the Anus muscle, the result being one developing a shitty attitude about every
thing ones eyes fall upon.

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